http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1301441-A

Outgoing Links

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-00
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filingDate 1970-01-20^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1972-12-29^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1301441-A
abstract 1301441 Preparation of methoxynaphthylpropionic acid and intermediates therefor SYNTEX CORP 20 Jan 1970 0 [30 Sept 1969] 31624/72 Divided out of 1300591 Headings C2B and C2C 2 - (6 - Methoxy - 2 - naphthyl) - propionic acid is prepared by reacting a compound of Formula I: R 1 B(R 2 )R 3 , where R 1 -R 3 are each 2 - (6 - methoxy - 2 - naphthyl) - 1 - propyl, alkyl, cycloalkyl or aralkyl at least one being the first mentioned radical; with CrO 3 in an aqueous solution of a lower alkanoic acid followed where desired by optical resolution. The compounds I are claimed per se and may be prepared by reaction of 6-methoxy-2-(2- propenyl)-naphthalene with diborane or a compound HBR 4 R 5 , where R 4 is H, alkyl, cycloalkyl or aralkyl and R 5 is alkyl, cycloalkyl or aralkyl. Pharmaceutical compositions comprising the 2 - (6 - methoxy - 2 - naphthyl) - propionic acid, when prepared by the above process, and an excipient are used in treating inflammation, pain and pyrexia.
priorityDate 1969-09-30^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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