| abstract |
The invention relates to plant extracts for stimulating the synthesis of hyaluronan synthase, in particular hyaluronan synthase 2 (HAS2), wherein said extract is of a plant chosen from Guarana (Paullinia cupana), St. John's wort (Hypericum hircinum), bamboo (Bambusa vulgaris), mung bean (Phaseolus aureus), gooseberry (Ribes uva-crispa L.), butcher's broom (Ruscus aculeatus), broad bean (Vicia faba equina), pea (Pisum sativum), lupin (lupinus angustifolius), Ephedra (Ephedra sinica), tansy (Tanacetum vulgare), Indian shell flower (Alpinia galanga), white mulberry (Morus alba), Youblie (Pentadiplandra brazzeana), and mixtures thereof. Cosmetic and pharmaceutical uses of these compositions to increase firmness, elasticity, tissue moisturization, and/or increase the skin barrier effect, increase tissue resilience, modulate angiogenesis, or the neocreation of blood capillaries, and/or improve healing, cell proliferation, migration or differentiation, skin atrophy, and/or to combat the effects of ageing on the skin, in particular loss of firmness of the skin observed in the course of ageing or atrophied scars are claimed. |