Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84364671cd083753f0062fd2960681e7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
2009-12-18^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dcb7aa05cd26d3a8de57cfcb4d32650 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a3ccd78afd8fefdda7ea197d7796a22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b787d0b91541bf748f114b0b18eaa3e2 |
publicationDate |
2011-06-22^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
GB-2476293-A |
titleOfInvention |
Therapeutic inhibition of ROR-1 |
abstract |
A biological inhibitor of ROR-1 capable of inducing cell death or apoptosis in a cell expressing ROR-1 may comprise an antibody or other agent with affinity for the extracellular domain of ROR-1 or may comprise an agent with affinity for a ROR-1 nucleic acid. The therapeutic inhibition of ROR-1 (receptor tyrosine kinase-like orphan receptor 1) in cancers, particularly CLL (chronic lymphocytic leukaemia) by RNAi or using antibodies is disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9266952-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012076727-A1 |
priorityDate |
2009-12-18^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |