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filingDate 2009-12-18^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dcb7aa05cd26d3a8de57cfcb4d32650
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publicationDate 2011-06-22^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2476293-A
titleOfInvention Therapeutic inhibition of ROR-1
abstract A biological inhibitor of ROR-1 capable of inducing cell death or apoptosis in a cell expressing ROR-1 may comprise an antibody or other agent with affinity for the extracellular domain of ROR-1 or may comprise an agent with affinity for a ROR-1 nucleic acid. The therapeutic inhibition of ROR-1 (receptor tyrosine kinase-like orphan receptor 1) in cancers, particularly CLL (chronic lymphocytic leukaemia) by RNAi or using antibodies is disclosed.
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