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filingDate 2018-05-24^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-11-27^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2574046-A
titleOfInvention Improved container
abstract A container for receiving a sample having cells in a fluid via a closable inlet 110 at a proximal end 104 and an outlet 118 having a breakable seal 120 for controlled dispensing of a lysed portion of the sample at a distal end 106, the container having at least one movable mechanical bead 122 located within the container between the inlet and outlet for mixing the sample when the container is manually moved, a reagent configured to lyse a cell and release nucleic acids from within the cell into the sample and at least one chemical bead 124 located within the container between the inlet and outlet for binding released nucleic acid, wherein said outlet, when exposed, is configured to controllably release at least the chemical bead through the outlet for deposition in a flowcell. The outlet is an end cap with a seal which is manually breakable by applying a torque force to the end cap. The outlet may comprise a funnel 114. The container may comprise a mechanical barrier (130;fig 7) to prevent the mechanical bead locating in the outlet.
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