abstract |
A column, such as a pipette tip column, comprised of a column body; an inlet on the column body; an outlet on the column body and a bed of medium comprising water-swollen beads, wherein the beads are compressible, and the bed of medium is not compressed. The bed of medium has a packing density, wherein the packing density is in the range 1.00-1.05. The beads are comprised of a capture entity, and the column is comprised of unrestricted flow channels, wherein the flow channels are sufficiently large for cells to pass through. Also disclosed is a method for passing a biological sample through the column. The biological sample is comprised of blood, urine, faeces, saliva, spinal fluid or semen. |