http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-874015-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d037bc74e34c7d73dd883f208aef0518 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-10 |
| filingDate | 1959-03-16^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab346977f93f9a3ccea22cc454cef668 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b536228c2bce8e4539ab74cfb9230c47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64cba436aed81c225930fa1c84583ade http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84491bcbee8b267378504a34d7f642e8 |
| publicationDate | 1961-08-02^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-874015-A |
| titleOfInvention | Tropine esters |
| abstract | The invention comprises racemic and optically active esters of the general formula <FORM:0874015/IV (b)/1> (wherein R represents a C1-C8 alkyl radical), and the preparation thereof by heating an equimolecular mixture of tropine and a racemic or optically active a -alkyl-O-acetyltropic acid chloride of the general formula <FORM:0874015/IV (b)/2> at 100-150 DEG C. in an inert organic solvent and splitting off the acetyl group with hydrochloric acid at room temperature. The products possess properties similar, but superior, to those of atropine. a -Alkyl-O-acetyltropic acid chlorides of the second general formula above are prepared by refluxing a -alkyltropic acids with acetic anhydride, and refluxing the resulting a -alkyl-O-acetyltropic acids with thionyl chloride. (-)- and (+)-Methyltropic acids are prepared by resolving DL-a -methyltropic acid with quinine and brucine respectively. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3290316-A |
| priorityDate | 1959-03-16^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Showing number of triples: 1 to 37 of 37.