http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-52294-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-80 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0222 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 |
filingDate | 1982-03-19^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1987-09-02^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IE-52294-B1 |
titleOfInvention | Dipeptides containing thialysine and homologs as antihypertensives |
abstract | The invention relates to dipeptide compounds containing thialysine and related amino acids of the formula: wherein nR and R2 are independently hydrogen, loweralkyl, aralkyl;nR1 is alkyl, substituted lower alkyl, aralkyl, aralkenyl, heteroaralkyl or heteroaralkenyl; substituted aralkyl, aralkenyl, heteroaralkyl, or heteroaralkenyl;nX is S, S→O or 0;nI is 1-2;nm is 2 - 3; is a grouping wherein:nA is cycloalkyl, aryl, aralkyl, heteroaryl or heteroaralkyl;nB is hydrogen or loweralkyl; ornA and B can be joined together to form ring structures; and the pharmaceutically acceptable salts thereof. Those compounds are useful as converting enzyme inhibitors and as antihypertensives. |
priorityDate | 1981-03-23^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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