Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56ee5285e8e8edccb061046ff20da7a6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B23K26-351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-535 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B23K26-351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
filingDate |
1991-04-23^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
1991-11-20^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
IE-911359-A1 |
titleOfInvention |
Muteins of the granulocyte colony stimulating factor |
abstract |
A granulocyte-stimulating factor (G-CSF) or G-CSF variant differs from natural G-CSF in that one or more amino acids in the sequence 50 51 52 53 54 55 56 Leu-Gly-His-Ser-Leu-Gly-Ile at position 50 to 56 of mature G-CSF with 174 amino acids or at position 53 to 59 of mature G-CSF with 177 amino acids and/or at least one of the 4 His residues at position 43, 79, 156 or 170 of mature G-CSF with 174 amino acids or at position 46, 82, 159 or 173 of mature G-CSF with 177 amino acids are mutated. It is suitable for immunotherapy. |
priorityDate |
1990-05-08^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |