http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-S86598-B2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4c6a2eb66d07fad39d708e5a36c9350
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
filingDate 2014-12-16^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7903cceec74ec596e60d5824e6cca45e
publicationDate 2015-11-18^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-S86598-B2
titleOfInvention An injectable antibody preparation for use in treating or reducing the risk of atopic dermatitis or asthma
abstract An injectable preparation comprising an antibody or antibody fragment for use in a method of treating or reducing the risk of atopic dermatitis or asthma in humans is described. The antibody or antibody fragment of the preparation specifically binds to a human IL4Ra protein that comprises a selected mutation. The antibody or antibody fragment comprises a VH domain derived from the recombination of a human VH segment, a human D gene segment and a human JH segment, the human VH segment of which encodes a specific framework 1 of SEQ ID NO: 40. The human may either comprise a VH gene segment encoding the framework 1, or express VH domains that comprise the framework 1. The human further comprises a nucleotide sequence encoding said IL4Ra protein comprising said selected mutation.
priorityDate 2014-08-29^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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