http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IL-47842-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2f3f56c2eb4eab834d912e9e9dc6513 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C275-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-23 |
| filingDate | 1975-07-30^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1980-07-31^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IL-47842-A |
| titleOfInvention | Nitroso urea glycosides and related compounds,their preparation and pharmaceutical compositions containing them |
| abstract | Nitrosourea derivatives of the formula <IMAGE> in which A is a glycosyl group, a monovalent radical of methyl glucoside from which the 2-hydroxy group has been removed, a monovalent radical of an alditol from which the 2-hydroxy group has been removed, an N-substituted carbamoyloxyalkyl group or a hydroxy-substituted cyclohexyl group when n equals 1, or a tetravalent radical of ribostamycin from which the four amino groups have been removed when n equals 4, and R is a lower alkyl group or a halogen-substituted lower alkyl group, with R not being a methyl group when A is a glucosyl group, are obtained by treatment of a compound of the formula <IMAGE> in which A, R and n have the same meaning as indicated above, with a nitrosating agent. The compounds have high activity against leukaemia and tumours, with low toxicity. |
| priorityDate | 1974-08-08^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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