| abstract |
PROBLEM TO BE SOLVED: To simulate important morphological and permeability characteristics of brain BBB, enable efficient and inexpensive screening of central nervous system drugs, and to test manipulation on BBB. To provide an in vitro model of the vertebrate BBB that allows for efficient and inexpensive central nervous system drug screening. A composition for preparing a medicament for preventing, ameliorating, or treating brain inflammation, comprising: A composition comprising at least one reagent that inhibits binding of an A-4 molecule to a VCAM-1 molecule. |