| abstract |
(57) The present invention relates to a compound represented by the formula (I) wherein A is a heteromonocyclic ring containing 5 to 6 ring members or a fused heteropolycyclic ring containing 8 to 14 ring members. Wherein each ring contains 5 to 7 ring members, X 1 is a ring carbon atom, and each ring member other than X 1 is a carbon atom or a heteroatom (provided that (i) The two ring atoms are heteroatoms and (ii) when A is a heteromonocyclic group containing 5 ring atoms, provided that no more than two of the ring atoms containing A are heteroatoms. N) is 0, 1, 2 or 3, X 1 is ＝ C— or —CH—, X 2 is a bond or a divalent group of formula (a) or (b), R 1 to R 8 are as in the present application) by a novel alkanoyl-substituted heterocyclic are cysteine protease inhibitors Conductors, their pharmaceutically acceptable salts and their N- oxides, their use as therapeutic agents, and methods for their preparation. |