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filingDate 2002-08-28^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c309126f4b26997eba10e9477a512145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8ce1e220fa8702865ad7105caaba1c8
publicationDate 2003-06-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2003159053-A
titleOfInvention Plasma prekallikrein activation method
abstract [PROBLEMS] To provide a known plasma prekallikrein activator. A novel method for activating plasma prekallikrein that activates plasma prekallikrein in the absence of FXIIa to produce plasma kallikrein, and a method for screening a drug using the same. The present invention relates to heat shock protein 90 (HS). FXIIa by plasma prekallikrein activator selected from the group consisting of P90) or phosphoric acid or a mixture thereof Is a method of activating plasma prekallikrein in the absence of E. coli. EFFECT OF THE INVENTION Using the activation method of the present invention, it is possible to measure the activity (promoting or inhibiting activity) of test drugs such as analgesics, antiallergic agents and antiinflammatory agents on plasma kallikrein production in the absence of FXIIa. it can.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11156612-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019502095-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11372002-B2
priorityDate 2001-08-29^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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