abstract |
(57) Abstract: Substituted phenanthrene-9,10-diones conforming to the chemical structural formula (I), and compositions thereof for the treatment of conditions involving T cells such as autoimmune disorders and organ transplant rejection How to use. In the compounds of the invention, R 1 is in each case hydrogen, halogen, NH-tosyl, N-di-tosyl, NH 2 , NO 2 , NH—CO—R 2 , CO—NH—R 2 , Ar, (CH 2) n CH (COOH) R 3, COR 3 and NHCOCH 2 CH (COOH) will be independently selected from NHR 4, wherein the definitive R 2, R 3 and R 4 are a substituted or unsubstituted alkyl and aryl groups and Select from oligopeptides. Embedded image |