http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004321015-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2003-04-22^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc939bb6faab164b0890076baa601500 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e73a5541c05e9d665cb23dcb174be03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0f845bed3645d1b84a1be72b69715be |
| publicationDate | 2004-11-18^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004321015-A |
| titleOfInvention | Model animals for accelerated aging and immunodeficiency |
| abstract | A gene-mutated animal useful as a model of a disease state such as aging promotion and immunodeficiency is widely provided. A non-human mammal, particularly a mouse, deficient in a gene encoding an APEX2 enzyme that is an AP endonuclease. It is prepared using ES cells in which the gene encoding the APEX2 enzyme has been replaced by a gene lacking its function. It exhibits growth retardation due to natural DNA damage, and is highly susceptible to damage due to the damage, and has a remarkable decrease in the number of immunocompetent cells. Useful. [Selection] Figure 2 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104273616-A |
| priorityDate | 2003-04-22^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Showing number of triples: 1 to 423 of 423.