| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6572ff5df928fd17340eb2a8cb6d8502 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/F16B37-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-18 |
| filingDate |
2005-02-14^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c02db35430c2be4e50eee8f97bc66a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba15f7d2f01f9fa2271a3eba2eeefe63 |
| publicationDate |
2005-09-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2005239718-A |
| titleOfInvention |
Novel process for the preparation of (7-methoxy-1-naphthyl) acetonitrile and its use in the synthesis of agomelatine |
| abstract |
The present invention provides a novel process for producing (7-methoxy-1-naphthyl) acetonitrile useful as an intermediate of pharmaceutical agomelatine. 7-Methoxy-1-tetralone is reacted with cyanoacetic acid in the presence of a catalyst to obtain a compound of formula (VII). The reaction is then carried out with a hydrogenation catalyst in the presence of an allyl compound to give a compound of formula (I). [Selection figure] None |
| priorityDate |
2004-02-13^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |