| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F3-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F3-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 |
| filingDate |
2004-10-22^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2007-05-10^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2007511477-A |
| titleOfInvention |
Citalopram manufacturing method |
| abstract |
A process for the preparation of citalopram and its pharmaceutically acceptable salts is described. It is obtained starting from 5-cyanophthalide by reaction with a mixture of 4-fluorophenyl magnesium halide and 3-dimethylaminopropyl magnesium halide. The resulting intermediate is shown below, where X is a halogen, preferably chlorine or bromine, which is cyclized without isolation. |
| priorityDate |
2003-10-28^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |