http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008148620-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c9446a65422eaca792040fe2b817fb5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-30 |
| filingDate | 2006-12-18^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed9c79f6e03d40e1abe4046a76786d7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77f45a0c56ebfdb4b6e42ec359df505a |
| publicationDate | 2008-07-03^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2008148620-A |
| titleOfInvention | Process for producing CMP-deaminoneuraminic acid |
| abstract | PROBLEM TO BE SOLVED: To provide an efficient mass synthesis method and purification method of CMP-deaminoneuraminic acid (CMP-KDN). In a method for enzymatically producing CMP-deaminoneuraminic acid (CMP-KDN) from cytidine 5'-triphosphate (5'-CTP) and deaminoneuraminic acid (KDN), CMP is used as the enzyme. Provided is a process for producing CMP-KDN using N-acetylneuraminic acid synthase (CMP-NeuAc synthetase). Moreover, the refinement | purification method of CMP-KDN which consists of process 1-4 is provided. (Step 1) A step of adding a divalent cation to a CMP-KDN-containing solution to precipitate coexisting phosphate, pyrophosphate, and nucleotide, (Step 2) a step of converting a nucleotide into a nucleoside by an alkaline phosphatase reaction, (Step 3) ) A step of precipitating CMP-KDN with an organic solvent; and (step 4) a step of recovering CMP-KDN. [Selection figure] None |
| priorityDate | 2006-12-18^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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