| abstract |
Modulators of chemokine receptor activity, certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions (such as allergic rhinitis, dermatitis, conjunctivitis and asthma) and rheumatoid arthritis and atherosclerotic arteries Compounds of formula (I) and (II) useful for the prevention or treatment of autoimmune diseases such as sclerosis (Wherein Q, X, E, G 1 , G 2 , R 2 , R 3 , R 4 , R 5 , R 6 and Z are as defined herein). The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases involving chemokine receptors. |