| abstract |
The present invention is directed to formula (I) wherein R 1 is hydrogen, lower alkyl, lower alkoxy, lower alkyl substituted by halogen or halogen; R is hydrogen or halogen; or R 1 And R together with the carbon atom to which they are attached is —CH═CH—CH═CH—; R 2 is hydrogen, lower alkyl, phenyl optionally substituted by halogen, or R 3 is substituted by hydrogen, lower alkyl, phenyl, benzyl, lower alkenyl, lower alkoxy, phenyloxy, benzyloxy, S-lower alkyl, halogen, CN, halogen Lower alkyl or O-lower alkyl substituted by halogen; R 4 is hydrogen or lower alkyl. Aryl is phenyl or naphthyl; n is 1, 2 or 3; m is 1 or 2; and pharmaceutically acceptable acid addition salts and tautomers thereof Regarding the sex body. It has been found that the compounds of formula (I) have a good effect on the 5-HT 5A receptor. Thus, the present invention provides the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of certain CNS disorders. |