| abstract |
Described are targeted binding agents directed against the antigen uPAR, and the use of such antibodies. In particular, fully human monoclonal antibodies directed against the antigen uPAR. Nucleotide sequences encoding heavy and light chain immunoglobulin molecules, and amino acid sequences comprising the molecules, in particular of FR1 to FR4 or CDR1 to CDR3, particularly across the framework region and / or complementarity determining region (CDR). Sequence corresponding to adjacent heavy and light chain sequences. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies. [Selection] Figure 1 |