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filingDate 2010-02-22^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2010-07-08^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2010148515-A
titleOfInvention Method for measuring hemoglobin A1c, enzyme used therefor and method for producing the same
abstract Provided are a method and a reagent kit for specific measurement using an enzyme without separating the glycated β-chain N-terminus of glycated hemoglobin. Screening for a protease that cleaves a glycated amino acid and / or a glycated peptide from a glycated β-chain N-terminus without substantially cleaving the glycated amino acid or glycated peptide from the glycated α-chain N-terminus of glycated hemoglobin or a fragment thereof And a reagent kit for specifically measuring the glycated β-chain N-terminal of glycated hemoglobin without using a separation operation by using the protease obtained by the above. Glycated hemoglobin glycated β chain N-terminal can be measured specifically without separation. [Selection figure] None
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priorityDate 2003-05-21^^<http://www.w3.org/2001/XMLSchema#date>
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID152754954
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP19386
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID124635665
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458396415
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP19385
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID426285439
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP62757
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP19628
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID11421
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID412290698
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP51588
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP23916

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