abstract |
The present invention relates to novel pyridinyl derivatives of formula (I), which are 5-HT receptor ligands, in particular 5-HT6 subtypes, and are therefore useful in the treatment of diseases where modulation of 5-HT activity is desired. , Y, Z, L, R 1 to R 11 , n, m, p, q, t are as defined herein. The present invention relates to novel pyridinyl derivatives, including pharmaceutically acceptable salts thereof. The invention also relates to methods for preparing such compounds, intermediates used in the preparation thereof, pharmaceutical compositions containing them, and their use in the treatment of central nervous system disorders such as schizophrenia. [Chemical 1] |