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filingDate 2009-04-09^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2011-05-26^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2011516517-A
titleOfInvention Purification strategies for direct nucleophilic means
abstract The present invention provides a new and advantageous process for the preparation and purification of chemical compounds such as pharmaceuticals. The process comprises a nucleophilic substitution reaction with moiety X, in which the leaving group L of substrate S is covalently added to the purified moiety M. This concept provides a convenient and time-saving approach to purify the desired S—X from unreacted precursors and by-products LM.
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID91331820
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP60042
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID451839851
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP22393
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID150192079
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ28504
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP60041
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP81423
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5311065
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9IBE5
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID13075
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID12155
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID232426
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID58260777
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID82385
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP01342
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID58260776
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP01340
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3674
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457633337
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP31297
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID424532667
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9IB11
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID1390
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9GMB3
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID280836
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID108873234
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID554243
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID779149
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25804
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ28632
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID280833
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP46407
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO13188
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID737737
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24241
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP08998
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID27346
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100009122

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