| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e85961bb2dd7bc5dc990953233d799e |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate |
2011-02-24^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_580c4ae1e06b832a6a1c9d4315212910
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c8a80389faf07401c1b2d77f139939d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d738a2c78e2605f7d388b895d4970d1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a8d6e77b029682538ae00286342198c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eeb7db762452c32e1dc6a6c0c684d2fe |
| publicationDate |
2012-09-10^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2012171947-A |
| titleOfInvention |
Cartilage regeneration promoter |
| abstract |
An object of the present invention is to provide a cartilage formation promoter that can promote cartilage regeneration and also suppress inflammation. The pharmaceutical composition comprises boharmin or a pharmaceutically acceptable salt thereof as an active ingredient. According to the cartilage regeneration-promoting agent comprising the harmine of the present invention or a pharmaceutically acceptable salt thereof as an active ingredient, inflammation is suppressed, chondrocytes are efficiently induced to differentiate into mature chondrocytes, and cartilage is protected and regenerated. To do. This cartilage regeneration-promoting agent is prophylactic against diseases or disorders caused by cartilage loss, specifically degenerative joint diseases such as knee joints and hip joints, and inflammation associated with cartilage reduction in rheumatoid arthritis. Can be used therapeutically. [Selection] Figure 7 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3792262-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11130755-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019537587-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018083157-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3318563-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7046063-B2 |
| priorityDate |
2011-02-24^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |