http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012521394-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2009-11-30^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-09-13^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2012521394-A |
| titleOfInvention | 9H-pyrrolo [2,3-B: 5,4-C '] dipyridine azacarboline derivative, its preparation and its therapeutic use |
| abstract | The present invention provides a novel 9H-pyrrolo [2,3-b: 5,4-c ′] dipyridineazacarboline of formula (I) wherein Z2, Z3 and Z4 are CH, CRa, CRs, or N R3 is H, Hal, CF3, CHF2, OH, alkoxy, NH2, NH (alkyl), N (alkyl) 2, C (O) Oalkyl, CONH (alkyl), CON (alkyl) 2, C1 -C10 alkyl, aryl, heteroaryl; R6 is heteroaryl; Ra is CONH2, CONHalkyl, CONHcycloalkyl, CONHheterocycloalkyl, CON (alkyl) 2, CON (alkyl) (heterocycloalkyl ), CONHN (alkyl) 2, C (O) heterocycloalkyl; Rs is H, Hal, OH, O-alkyl (C 1-C10), NH2, N (alkyl (C1-C10) or cycloalkyl (C3-C7)) 2, NHC (O) R3a, N (alkyl (C1-C10) C (O) R3a, NHS (O2) R3a, N (alkyl (C1-C10) S (O2) R3a, CO2R3a, SR3a, S (O) R3a, S (O2) R3a; Ra and Rs optionally form a ring; R3a is Hal CF3, C1-C10 alkyl, C3-C7 cycloalkyl, C2-C6 alkenyl, C2-C6 alkynyl, OH, O-alkyl (C1-C10), (C3-C7), heterocycloalkyl (C3-C7), NH2, NH- (alkyl (C1-C10) or cycloalkyl (C3-C7)), N (alkyl (C1-C10) or cycloalkyl (C3-C7) ) 2, NH- (alkyl (C1-C10) or heterocycloalkyl (C3-C7)), N (alkyl (C1-C10) or heterocycloalkyl (C3-C7)) 2].] And the isomers and salts of the substances of formula (I) above and their therapeutic use for treating cancer. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101561330-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013514315-A |
| priorityDate | 2009-03-24^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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