abstract |
Provided is a means for simultaneously regulating the expression of two or more genes in the same cell. Several gene expression cassettes have been constructed for use in a multi-inducible gene expression system. This method is useful in applications where multiple gene regulation is important. That is, it overcomes the drawbacks in the field of gene expression and is useful in the fields of functional genomics, proteomics, metabolomics, toxicity screening, cell-based high-throughput screening assays, protein production and gene therapy. Provides a means for parallel control of multiple genes in the same cell, enabling one skilled in the art to analyze complex biological phenomena involving multiple genes or pathways and create new therapeutic applications To do. It relates to the field of biotechnology or genetic engineering. More particularly, the present invention relates to a multi-inducible gene regulatory system that functions in a cell to simultaneously control quantitative expression of multiple genes. [Selection figure] None |