| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aea5ddac9cae108a5f80101c3f50a351 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-42 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-88 |
| filingDate |
2012-11-07^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43f520fe98366eb70342749c2e74c5fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c620bf234bac17bea404ebccbc99f3d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceae4fb6f0d983e53e391c63fa8e6798
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6eb38c57f88c913c4cff58699fb9a67a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b9bb8fedfdc7659cdf84388726f515a |
| publicationDate |
2013-05-30^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2013103935-A |
| titleOfInvention |
Selective process for producing (+)-cis-sertraline |
| abstract |
The present invention provides a method for selectively producing (+)-cis-sertraline represented by the following formula 1 used as an intermediate in the production of sertraline hydrochloride. The present invention relates to reacting (±) -cis / trans-sertraline or (±) -cis-sertraline with (S)-(−)-2-pyrrolidone-5-carboxylic acid to give (+) −. Provided is a method for producing (+)-cis-sertraline represented by the formula 1, which comprises the step of producing cis-sertraline (S)-(−)-2-pyrrolidone-5-carboxylate and optically resolving. [Formula 1] [Selection figure] None |
| priorityDate |
2011-11-10^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |