| abstract |
The present invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods of using the compounds. [Solution] Pyrimidine and pyridine derivatives represented by In response to inhibition of its anaplastic lymphoma kinase (ALK) activity, adhesion plaque kinase (FAK), zeta chain-related protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R) or combinations thereof Use to treat, ameliorate, or prevent. [Selection figure] None |