| abstract |
The present invention relates to a peptide antagonist of a class III semaphorin / neuropilin complex, a nucleic acid encoding the peptide antagonist, a pharmaceutical composition comprising the peptide antagonist or a nucleic acid encoding the peptide antagonist, and use thereof. A protein selected from the group consisting of neuropilin-1, neuropilin-2, plexin-A1, plexin-A2, plexin-A3, plexin-A4, Nr-CAM, L1-CAM, integrin β1, and integrin β2. By including the amino acid sequence derived from the transmembrane domain of at least one GxxxG motif and finally fusing to a heterologous sequence. [Selection] Figure 2 |