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publicationDate 2013-02-04^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2013503853-A
titleOfInvention Method for treating neurodegenerative or neuro-muscular degenerative disease and therapeutic agent thereof
abstract Disclosed are compositions and methods for preventing, eliminating, treating and managing neurodegenerative or neuro-muscular degenerative disorders and diseases in humans or animals. Neurodegeneration and neuro-muscular degeneration disorders and diseases, particularly amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), Alzheimer's disease (AD), Parkinson's disease (PD), muscular dystrophy (MD) Disclosed is the use of therapeutically high doses of ascorbic acid or derivatives thereof of 1 gram or more daily. Preferably, the dose includes mannitol that facilitates the supply of ascorbic acid to the target cells in the brain. In addition, the dose includes zinc citrate to prevent the formation of kidney stones. Compositions in doses for various administration routes such as oral administration, intravenous administration, intramuscular administration, nasal, transdermal patch type, etc. have been described.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016074708-A
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