http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014065725-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ce7e5ae3b93c05abe32afc08089aabe |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate | 2013-12-02^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44df72b4179167c2316c2cf7a28f9e9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8088b5684fecd438342b9c4bb17de51 |
| publicationDate | 2014-04-17^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2014065725-A |
| titleOfInvention | Improved methods and compositions for F-18 labeling of proteins, peptides, and other molecules |
| abstract | Kind Code: A1 A useful F-19 labeled molecule composition, method of synthesis, and method of use for labeling a target moiety quickly and easily with positron emission tomography (PET) imaging technology. The labeled molecule may be a peptide, protein, aptamer or the like, and other types of molecules may be labeled and used. A metal complex may be formed and attached to a chelating moiety such as DOTA to conjugate the F-19 label to the targeting molecule. The metal may be conjugated first to the chelating group and then F-19 to the metal. F-19 labeling moieties are obtained in combination with bispecific or multispecific antibodies to target F-19 to antigens expressed in cells or tissues associated with disease, medical conditions, or pathogens Possible conjugates may be included. The F-19 labeled targetable conjugate peptide is stable in human serum for several hours at 37 ° C. [Selection figure] None |
| priorityDate | 2007-12-19^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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