abstract |
The present invention provides a novel compound as an estrogen-related receptor modulator, which is used for treating metabolic disorders such as high blood fat, fatty liver, hyperglycemia, diabetes, obesity and the like. A compound of formula I, a pharmaceutically acceptable salt thereof, or a stereoisomer thereof. (A, B, D and E are independently CH or N; n is 0 to 2; a and b are 0 or 1; R 1 is H, halogen, hydroxyl group, nitro group, carboxyl group, cyano group, ester group. , etc. may amido group which may be substituted; R 2 is H, an alkyl group, an allyl group, a heterocyclic; R 3 is H, halogen, hydroxyl, nitro, carboxyl group, cyano group, an ester group, substituted Good amide group) [Selection] Figure 1 |