| abstract |
Provided are compositions and methods for the treatment of denatured α-synuclein function. Compositions and methods are provided for treating α-synuclein dysfunction and / or disorders characterized by altered lipid metabolism. The present invention describes a method for modulating α-synuclein function, lipid metabolism and lysosomal storage by using agents that modulate α-synuclein function, lysosomal storage and lipid metabolism, particularly glycosphingolipid metabolism. . The present invention describes a method of modulating α-synuclein and lipid metabolism for the treatment of disease. [Selection figure] None |