| abstract |
Compounds and methods for treating anti-inflammatory conditions are provided. A compound having a structure according to the following formula and a salt thereof. (Ra is selected from CN, C (O) NR1R2, C (O) OR3, R3 is selected from H and substituted or unsubstituted alkyl, X is selected from N, CH and CRb, and Rb is Selected from halogen and substituted or unsubstituted alkyl, C (O) R4, C (O) OR4, OR4, NR4R5, wherein R1, R2, R4 and R5 are each H, substituted or unsubstituted, alkyl, heteroalkyl, cyclo Independently selected from alkyl, heterocycloalkyl, aryl, and heteroaryl, provided that R 1 and R 2 are optionally joined together with the atoms to which they are attached to form a 4-8 membered substituted or unsubstituted hetero Forms a cycloalkyl ring, and R4 and R5, together with the atoms to which they are attached, are optionally joined to form a 4-8 membered substituted or unsubstituted heterocycloalkyl. To form.) [Selection figure] None |