| abstract |
Disclosed are a compound and an HDAC8 inhibitor that are highly active and can selectively inhibit the function of HDAC8. The hydroxamic acid derivative of the invention is characterized by comprising the following general formula (1) or a pharmaceutically acceptable salt, hydrate, solvate or prodrug thereof. These hydroxamic acid derivatives (1) can selectively inhibit the enzymatic activity of HDAC8. [Selection figure] None |