| abstract |
[PROBLEMS] To treat, prevent, delay the time to onset or the occurrence of a disease or condition (including type 1 diabetes and type 2 diabetes, insulin resistance and hyperglycemia) exhibited by a plurality of glucagon receptor antagonists. Or provide a method to reduce the risk of progression. A pharmaceutical composition comprising a compound having a glucagon receptor antagonist or inverse agonist activity exemplified by the following formula. [Selection figure] None |