| abstract |
In one aspect, the invention relates to a compound having the formula (I), wherein R 1 to R 5 and X are as defined herein, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibitory activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds. The compounds of the present invention are expected to be useful and advantageous as therapeutic agents for treating conditions such as hypertension and heart failure. |