| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea1fff38e27d2aa34504ab65f60e7631 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-36 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 |
| filingDate |
2017-03-06^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b001ace97d9bdd5b6bb5df5a1dbfa499
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b25b54602edce75c08be3b7cd309ffd1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bebe7c9723d8bab4fc777caa7166e54c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69255d21107201275b616623164e6938 |
| publicationDate |
2017-08-17^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2017141237-A |
| titleOfInvention |
Method for producing botulinum toxin |
| abstract |
PROBLEM TO BE SOLVED: To provide a method for producing botulinum toxin. (A) A step of acidifying a botulinum toxin-producing strain culture solution with an acid to precipitate the botulinum toxin; (b) adding a buffer solution to the precipitated botulinum toxin And (c) treating the extracted botulinum toxin with an acid to acid-precipitate the botulinum toxin, and then subjecting the precipitate to a buffer solution. And (d) a step of purifying the botulinum toxin using anion exchange chromatography. Preferably, the purified botulinum toxin is a botulinum toxin type A protein having a purity of 98% or more. [Selection] Figure 1 |
| priorityDate |
2013-08-02^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |