| abstract |
The present application relates to novel substituted piperidinylpyrazolopyrimidinones, methods of preparing them, methods of treating and / or preventing diseases, particularly basic hereditary or acquired hemostatic disorders. The compound for use alone or in combination in a method of treating and / or preventing acute and recurrent bleeding in patients with or without Menstrual bleeding, postpartum hemorrhage, hemorrhagic shock, hemorrhagic cystitis, gastrointestinal bleeding, trauma, surgery, transplant, stroke, liver disease, hereditary angioedema, nosebleed, and synovitis and cartilage after arthremia Associated with a disease or medical intervention selected from the group consisting of injuries. |