| abstract |
Human protein tyrosine phosphatase inhibitors and methods of use are provided. The present disclosure relates to compounds that are effective as human protein tyrosine phosphatase β (HPTP-β) inhibitors, thereby controlling angiogenesis. The present disclosure further relates to a composition comprising the human protein tyrosine phosphatase β (HPTP-β) inhibitor and a method of controlling angiogenesis. Diseases to be treated by the composition of the present invention include diabetic retinopathy, macular degeneration, cancer, sickle cell anemia, sarcoma, syphilis, elastic fiber pseudoxanthoma, Paget's disease, vein occlusion, arterial occlusion, Carotid artery occlusive disease, chronic uveitis / vitreitis, mycobacterial infection, etc. [Selection figure] None |