http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018076351-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06
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filingDate 2017-12-21^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d8e55efd9259af28537fad4ce665782
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publicationDate 2018-05-17^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2018076351-A
titleOfInvention Methods for treating homozygous familial hypercholesterolemia
abstract A method for treating homozygous familial hypercholesterolemia is provided. An antibody (anti-PCSK9 antibody) against a proprotein convertase subtilisin / kexin type 9 (PCSK9), comprising a light chain containing a specific amino acid sequence and a heavy chain containing a specific amino acid sequence, is homozygous. A dosage of about 120 mg to about 3000 mg is administered to a patient diagnosed with sex familial hypercholesterolemia. The anti-PCSK9 antibody is (1) once a week, (2) once every two weeks, (3) once a month, (4) once every three months, (5) once every six months. And (6) administering to the patient on a schedule selected from the group consisting of once every 12 months. [Selection figure] None
priorityDate 2017-12-21^^<http://www.w3.org/2001/XMLSchema#date>
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