| abstract |
The present invention relates to a method for separating Trolox isomers (R) -Trolox and (S) -Trolox, wherein a mixture of (a) (R) and (S) -Trolox is (1S, 2S )-(+)-Pseudoephedrine, (R)-(+)-2-amino-3-phenyl-1-propanol, (1R, 2R)-(−)-pseudoephedrine, and (S)-(−)-2. Contacting with a resolving agent selected from the group consisting of: amino-3-phenyl-1-propanol, wherein the resolving agent is solid with one of (R) -Trolox and (S) -Trolox Forming a salt and substantially not forming a solid salt with the other; and (b) separating the solid salt from the Trolox isomer that did not form a solid salt with the resolving agent. |