| abstract |
PROBLEM TO BE SOLVED: To provide a novel pharmaceutical composition having improved delivery and efficacy of a therapeutically active ingredient to a target tumor site in cancer treatment. A composition for treating cancer in an individual, the composition comprising nanoparticles comprising taxane and albumin, wherein the cancer has a dense stroma and the cancer is mesothelioma. , A composition selected from the group consisting of tendonoid fibroma and fibrogenic round cell tumor. Preferably, the nanoparticles include a taxane coated with albumin. The composition is preferably administered in combination with another therapeutic agent selected from the group consisting of antimetabolites such as gemcitabine, platinum-based substances such as carboplatin and prednisone. [Selection diagram] None |