http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020143042-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_850a17186ff51f03c607cf42a534a635 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4468 |
| filingDate | 2020-01-16^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cd186a7d8492a89817b2b270b2b0eb7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bd4fffc54a7b5f829772ce39a20db8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7304477cefe04f0d9665360e710d4513 |
| publicationDate | 2020-09-10^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2020143042-A |
| titleOfInvention | Transdermal preparation |
| abstract | PROBLEM TO BE SOLVED: To provide a fentanyl-containing transdermal preparation capable of reducing a decrease in analgesic effect occurring on the third day after application. According to the present invention, a support, a drug-containing layer laminated on the support, a drug control membrane laminated on the drug-containing layer and permeable to the drug, and a drug control membrane. In a transdermal formulation having a laminated adhesive layer, The drug-containing layer comprises a pressure-sensitive adhesive and drug-containing particles containing fentanyl or a pharmaceutically acceptable salt thereof and a solubilizer dispersed in the pressure-sensitive adhesive. When the transdermal preparation is applied to the skin for 72 hours, the time elapsed from the application of the transdermal preparation is 48 to 72 hours in the blood of fentanyl or a pharmaceutically acceptable salt thereof. concentration not less than 0.2 ng / mL, the coefficient of variation of AUC 48-72 of fentanyl or a pharmaceutically acceptable salt thereof to provide a percutaneous preparation 35% or less. [Selection diagram] Fig. 1 |
| priorityDate | 2019-02-28^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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