http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020536060-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-609 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7115 |
filingDate | 2018-09-28^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-12-10^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2020536060-A |
titleOfInvention | Combination therapy to treat muscular dystrophy |
abstract | The present disclosure relates to a method of treating Duchenne muscular dystrophy by administering antisense oligonucleotides and non-steroidal anti-inflammatory compounds that induce exon skipping. The present disclosure induces or increases dystrophin protein production in patients with DMDs who have a mutation in the Duchenne muscular dystrophy (DMD) gene suitable for exon 51 skipping and who need to induce or increase dystrophin protein production. A method is provided that comprises administering to the patient an effective amount of eteprylsen and an effective amount of a non-steroidal anti-inflammatory compound, thereby inducing or increasing dystrophin protein production in the patient. |
priorityDate | 2017-09-28^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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