| abstract |
PROBLEM TO BE SOLVED: To provide a method for prognostic diagnosis and treatment of cancer metastasis. The present invention relates to a method for prognostic diagnosis of bone metastases in triple negative (including basal cell-like) breast cancer or or ER + breast cancer (including luminal A and β), the method of which is in a primary tumor sample. Includes the step of determining if the c-MAF gene of Similarly, the invention relates to a method for determining the propensity to develop bone metastases with respect to metastases in other organs, the method comprising determining the expression level, amplification or translocation of the c-MAF gene. .. The present invention also relates to methods for predicting early bone metastases in subjects suffering from breast cancer. [Selection diagram] None |