http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021508341-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 |
| filingDate | 2018-12-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-04^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2021508341-A |
| titleOfInvention | Pharmaceutical compound |
| abstract | Benzimidazole derivative of formula (I): (formula (I)) in formula: R1 is-(CH2) m-R7, (formula (II)) or (formula (III)); R2 is H, Halo,-(CH2) m-NH2,-(CH2) nC (= NH) -NH2 or-(CH2) n-NH- (CH2) m-NHR9; R3 is H, F or Cl; R4, R5 and R6 are H or F independently; R7 is C1-C6 alkyl, CF3, -SO2R11, -NH- (CH2) 2- (NH) r-R8, -NH-CH (R8R9) or the following formula (A): is the basis of (formula (A)): W is-(CH2) m-, -CH2-O-CH2-, -CH2-S-CH2-,-(CH2) ) RS (O) 2-CH2- or-(CH2) r-NR8-CH2-; m is an integer 1-3; n is 1 or 2; p is 1 and V Is CH; or p is 0 and V is N; q is 0 or 1; r is 0 or 1; R8 is H, -SO2R11, -SO2CF3, -COR11, -C (O) OR11, -CON (R9) 2 or-(CH2) nSO2 R11; R9 is H or C1-C6 alkyl, each R9 is the same or different if there are two; R10 is -SO2R11, -SO2CF3, -COR11, -CON (R9) 2 or-(CH2) nSO2R11; and R11 is C1-C6 alkyl; and its pharmaceutically acceptable salt is an inhibitor of RSV. Yes, and can therefore be used to treat or prevent RSV infection. [Selection diagram] None |
| priorityDate | 2017-12-22^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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