http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03106873-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18a7d1606da2ec2ad08ae63822efb00e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 |
| filingDate | 1989-09-20^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aef3c459adcac86b7ed1adb700ef5392 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6530795c59f117490f62a4a12d9ccb55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46ba7135935f0f01429ad99df35925c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efdeb09ab931fd71e4108f94fce8457b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d9bed76d7eb215b8467952d1114802e |
| publicationDate | 1991-05-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03106873-A |
| titleOfInvention | 1-pyridylphthalazine derivative and inhibitor of blood platelet agglutination containing same derivative |
| abstract | NEW MATERIAL:A compound shown by formula I [pyridyl substitution position is any position of 2-, 3- and 4-positions; R 1 is H or methoxy; Y is phenyl shown by formula II (R 3 is lower or middle alkyl, halogen, phenyl which may be replaced with cyano or pyrimidinyl; R 3 is H, lower alkyl or bonded into R 2 -N-R 3 to form piperidino or morpholino) or group shown by formula -X-R 2 (X is O or S)]. n EXAMPLE: 1-Anilino-4-(3-pyridyl)phthalazine. n USE: An inhibitor of blood platelet agglutination having more excellent activity than aspirin and useful for preventing and remedying cerebral thrombosis, cerebral infarct, peripheral arterial atresia, etc. n PREPARATION: A 1-pyridyl-4-chlorophthalazine derivative shown by formula III is reacted with an amine, alcohol, phenol, mercaptan or thiophenol in a solvent such as methylene chloride in the presence of a base (e.g. sodium carbonate) at 50-200°C to give a compound shown by formula I. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5324727-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0682947-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007536276-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0005218-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5462941-A |
| priorityDate | 1989-09-20^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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