abstract |
(57) [Summary] (Corrected) [Configuration] The following formula [In the formula, R is H or CH 3 , R 1 and R 2 are H, CH 3 -, CH 3 CH 2 -, etc., R a is hydrogen, trifluoromethyl group, a halogen atom, M is hydrogen, an esterifying group which can be used pharmaceutically, indicating, for example, carboxyl protecting groups which may be removed] (wherein 2-Fluoren-9-one or 3-fluoren-9-one is bonded to the 2-position of the carbapenem) and an intermediate for synthesis thereof. [Effect] Methicillin-resistant Staphylococcus aureus (MRS) A), methicillin-resistant Staphylococcus aureus (MRSE), methicillin-resistant coagulase-negative staphylococcus (MRCN) It has a strong effect on S). |